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Information was collected from prescriptions retained in pharmacies and manual records. The incomplete record of the name of patients and the different criteria of cataloging records determined the exclusion of some cases. We should also consider that only the prescriptions dispensed are retained in the pharmacies of these units.
Patients may have received other prescription of drugs subject to special control, not present in REMUME, or of special or specialized component of the pharmaceutical care.
Settembre | | Carlo Favaretti
Despite these limitations, this study brings contributions, as the Brazilian data on the use of unlicensed and off-label medicines in children are so far restricted to hospitals.
The difficulties related to research with children foster off-label prescribing.
Although this practice is not illegal, it creates uncertainty regarding the possible adverse effects in a population with specific characteristics such as the pediatric population. The present study showed that this practice is common in primary health care in a city of Rio Grande do Sul, similar to studies in European cities.
We hope that the results may contribute to the planning of actions to support prescribers and provide greater security in the use of medicines for pediatric patients. Footnotes The study received no funding. References 1.
J Pediatr Rio J ;— Fuchs FD, Wanmacher L. Rio de Janeiro: Guanabara Koogan; Incidence of unlicensed and off-label prescription in children. Ital J Pediatr. Unlicensed and off label prescribing of drugs in general practice. Arch Dis Child. Italian paediatricians and off-label prescriptions: loyal to regulatory or guideline standards.
Acta Paediatr. Off-label use of prescription drugs in childhood and adolescence. Dtsch Arztebl Int. Off label use of prescription medicines in children in outpatient setting in Estonia is common.
prontuario farmaceutico nazionale pdf to excel
Pharmacoepidemiol Drug Saf. Rev Assoc Med Bras.
Dos Santos L, Heineck I. Drug utilization study in pediatric prescriptions of a university hospital in southern Brazil: off-label, unlicensed and high-alert medications.
Farm Hosp. Off-label and unlicensed drug utilization in hospitalized children in Fortaleza, Brazil. Eur J Clin Pharmacol. Off-label prescribing to children in primary care: retrospective observational study.
prontuario farmaceutico 2012 pdf
Unlicensed and off-label prescription of respiratory drugs to children. Eur Respir J.
Paediatric drug use with focus on off-label prescriptions in Swedish outpatient care — a nationwide study. Rev Saude Publica. Off label and unlicensed drug use among French office based paediatricians. Cad Saude Publica. World Health Organization. Promoting rational use of medicines: core components.
Geneva: WHO; Utility of routinely acquired primary care data for paediatric disease epidemiology and pharmacoepidemiology. Br J Clin Pharmacol. Off-label prescribing of inhaled corticosteroids to children with asthma in primary care.
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Antibiotic prescribing for children. Too much and too little? Retrospective observational study in primary care. Off-label prescribing for allergic diseases in Children.Cad Saude Publica ; 25 S3 : Jump to. Risk factors for adverse drug events among older adults in the ambulatory setting. Rational use of medicines: prescribing indicators at different levels of health care.
A review of loratadine in the treatment of patients with allergic bronchial asthma.
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